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AlphaFold

The AI system that predicts protein shapes, a landmark scientific use of AI.

AlphaFold is an AI system developed at Google DeepMind that predicts the three-dimensional shape of proteins from their genetic sequence. Understanding these shapes is crucial to biology and medicine, because a protein’s form largely determines what it does.

The problem had resisted scientists for about fifty years. AlphaFold’s breakthrough was significant enough that its lead researcher, John Jumper, shared a Nobel Prize for the work, and the system’s predictions have been made freely available to researchers worldwide.

AlphaFold is often cited as the clearest proof that AI can do real scientific work, not just answer questions — accelerating discovery in fields like drug development and disease research.